Member: September 2015 - December 2019

Research interest
pathogen-host interactions, immunomodulation, parasitology

Title of PhD project
Giardia duodenalis - Dendritic cell interaction and intestinal barrier function

Supervisors
Dr. Anton Aebischer and Prof. Dr. Jörg-Dieter Schulzke

Weiß F, Holthaus D, Kraft M, Klotz C, Schneemann M, Schulzke JD, Krug SM. (2022).
Human duodenal organoid-derived monolayers serve as a suitable barrier model for duodenal tissue.
Ann N Y Acad Sci 1515:155-67. doi: 10.1111/nyas.148045.

Holthaus D*, Kraft MR*, Krug SM, Wolf S, Müller A, Delgado Betancourt E, Schorr M, Holland G, Knauf F, Schulzke JD, Aebischer T^§, Klotz C^§. (2022).
Dissection of barrier dysfunction in organoid-derived human intestinal epithelia induced by Giardia duodenalis.
Gastroenterology 162:844-58. doi: 10.1053/j.gastro.2021.11.022. *^/§equal contribution

Kraft MR, Klotz C, Bücker R, Schulzke JD, Aebischer T. (2017).
Giardia's Epithelial Cell Interaction In Vitro: Mimicking Asymptomatic Infection?
Front Cell Infect Microbiol 7:421. doi: 10.3389/fcimb.2017.00421.