Prof. Frank Mockenhaupt
Project C7 (former B2): Evidence for Plasmodium falciparum artemisinin resistance in sub-Saharan Africa based on molecular markers and in vitro and in vivo findings: PhD students: Costanza Tacoli (B2-1), Welmoed van Loon (C7-2) and Megan Peedell (C7-3).
Charité – Universitätsmedizin Berlin
Institute of Tropical Medicine and International Health
Research interest:
- Tropical Diseases
- Infectious Disease Epidemiology
van Loon W, Oliveira R, Bergmann C, Habarugira F, Tacoli C, Jäger J, Savelsberg D, Mbarushimana D, Ndoli JM, Sendegeya A, Bayingana C, Mockenhaupt FP. (2023).
Plasmodium vivax Malaria in Duffy-Positive Patients in Rwanda.
Am J Trop Med Hyg 109:621-3. doi: 10.4269/ajtmh.23-0143.
van Loon W, Oliveira R, Bergmann C, Habarugira F, Ndoli J, Sendegeya A, Bayingana C, Mockenhaupt FP. (2022).
In Vitro Confirmation of Artemisinin Resistance in Plasmodium falciparum from Patient Isolates, Southern Rwanda, 2019.
Emerg Infect Dis 28:852-5. doi: 10.3201/eid2804.212269.
Siegert K, van Loon W, Gai PP, Rohmann JL, Piccininni M, Näher AF, Boloor A, Shenoy D, Mahabala C, Kulkarni SS, Kumar A, Wedam J, Gai P, Devi R, Jain A, Kurth T, Mockenhaupt FP. (2021).
The Effect of Socioeconomic Factors and Indoor Residual Spraying on Malaria in Mangaluru, India: A Case-Control Study.
Int J Environ Res Public Health 18:11853. doi: 10.3390/ijerph182211853.
van Loon W, Bergmann C, Habarugira F, Tacoli C, Savelsberg D, Oliveira R, Mbarushimana D, Ndoli J, Sendegeya A, Bayingana C, Mockenhaupt FP. (2021).
The Changing pattern of Plasmodium falciparum multi-drug resistance-1 gene polymorphisms in southern Rwanda.
Antimicrob Agents Chemother 65:e0090121. doi: 10.1128/AAC.00901-21.
Bergmann C, van Loon W, Habarugira F, Tacoli C, Jäger JC, Savelsberg D, Nshimiyimana F, Rwamugema E, Mbarushimana D, Ndoli J, Sendegeya A, Bayingana C, Mockenhaupt FP. (2021).
Increase in Kelch 13 Polymorphisms in Plasmodium falciparum, Southern Rwanda.
Emerg Infect Dis 27:294–6. doi: 10.3201/eid2701.203527.
van Loon W, Gai PP, Kulkarni SS, Rasalkar R, Siegert K, Wedam J, Boloor A, Baliga S, Kumar A, Jain A, Mahabala C, Shenoy D, Devi R, Gai P, Mockenhaupt FP. (2020).
MiRNA-146a polymorphism was not associated with Malaria in Southern India.
Am J Trop Med Hyg 102:1072-4. doi: 10.4269/ajtmh.19-0845.
Gai PP, van Loon W, Siegert K, Wedam J, Kulkarni SS, Rasalkar R, Boloor A, Kumar A, Jain A, Mahabala C, Baliga S, Devi R, Shenoy D, Gai P, Mockenhaupt FP. (2019).
Duffy antigen receptor for chemokines gene polymorphisms and malaria in Mangaluru, India.
Malar J 18:328. doi: 10.1186/s12936-019-2966-9.
van Loon W, Gai PP, Hamann L, Bedu-Addo G, Mockenhaupt FP. (2019).
MiRNA-146a polymorphism increases the odds of malaria in pregnancy.
Malar J 18:7. doi: 10.1186/s12936-019-2643-z.
Tacoli C, Gai PP, Siegert K, Wedam J, Kulkarni SS, Rasalkar R, Boloor A, Jain A, Mahabala C, Baliga S, Shenoy D, Gai P, Devi R, Mockenhaupt FP. (2019).
Characterization of Plasmodium vivax pvmdr1 polymorphisms in isolates from Mangaluru, India.
Am J Trop Med Hyg 101:416-7. doi: 10.4269/ajtmh.19-0224.
Wedam J, Tacoli C, Gai PP, Siegert K, Kulkarni SS, Rasalkar R, Boloor A, Jain A, Mahabala C, Baliga S, Shenoy D, Devi R, Gai P, Mockenhaupt FP. (2018).
Molecular evidence for Plasmodium falciparum resistance to sulfadoxine-pyrimethamine but absence of K13 mutations in Mangaluru, southwestern India.
Am J Trop Med Hyg 99:1508-10. doi: 10.4269/ajtmh.18-0549.
Tacoli C, Gai PP, Bayingana C, Sifft K, Geus D, Ndoli J, Sendegeya A, Gahutu JB, Mockenhaupt FP. (2016).
Artemisinin Resistance-Associated K13 Polymorphisms of Plasmodium falciparum in Southern Rwanda, 2010-2015.
Am J Trop Med Hyg 95:1090-3. doi: 10.4269/ajtmh.16-0483.
