Jun.-Prof. Friederike Ebner
Project C9: The role of antigen-specific T cells in parasite distribution and predisposition to Ascaris suum in pigs:
PhD student Larissa Oser (C9-3)
Freie Universität Berlin
Department of Veterinary Medicine
Institute of Immunology
Research Interest
- Immunological reactions in parasite infections
Mugo RM, Rausch S, Musimbi ZD, Strube C, Raulf MK, Landt O, Gichuki PM, Ebner F, Mwacharo J, Odiere MR, Ndungu FM, Njomo DW, Hartmann S. (2024).
Evaluation of copromicroscopy, multiplex-qPCR and antibody serology for mon-itoring of human ascariasis in endemic settings.
PLOS Negl Trop Dis 18:e0012279. doi: 10.1371/journal.pntd.0012279.
Oser L, Midha A, Schlosser-Brandenburg J, Rausch S, Mugo RM, Kundik A, Elizalde-Velázquez LE, Adjah J, Musimbi ZD, Klopfleisch R, Helm CS, von Samson-Himmelstjerna G, Hartmann S, Ebner F. (2024).
Ascaris suum infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion.
Front Immunol 15:1396446. doi: 10.3389/fimmu.2024.1396446.
Kundik A, Musimbi ZD, Krücken J, Hildebrandt T, Kornilov O, Hartmann S, Ebner F. (2023).
Quantifying metabolic activity of Ascaris suum L3 using resazurin reduction.
Parasit Vectors 16:243. doi: 10.1186/s13071-023-05871-5.
Hamid B, Ebner F, Bechtold L, Kundik A, Rausch S, Hartmann S. (2022).
Ascaris suum excretory/secretory products differentially modulate porcine dendritic cell subsets.
Front Immunol 13:1012717. doi: 10.3389/fimmu.2022.1012717.
Kapse B, Zhang H, Affinass N, Ebner F, Hartmann S, Rausch S. (2022).
Age-dependent rise in IFN-γ competence undermines effective type 2 responses to nematode infection.
Mucosal Immunol Jun 11. doi: 10.1038/s41385-022-00519-6.
Schlosser-Brandenburg J, Ebner F, Klopfleisch R, Kühl AA, Zentek J, Pieper R, Hartmann S. (2021).
Influence of Nutrition and Maternal Bonding on Postnatal Lung Development in the Newborn Pig.
Front Immunol 12:734153. doi: 10.3389/fimmu.2021.734153.
Hamid B, Schlosser-Brandenburg J, Bechtold L, Ebner F, Rausch S, Hartmann S. (2021).
Early Immune Initiation by Porcine Cells following Toxoplasma gondii Infection versus TLR Ligation.
Microorganisms 9:1828. doi: 10.3390/microorganisms9091828.
Yordanova IA, Ebner F, Schulz AR, Steinfelder S, Rosche B, Bolze A, Paul F, Mei HE, Hartmann S. (2021).
The Worm-Specific Immune Response in Multiple Sclerosis Patients Receiving Controlled Trichuris suis Ova Immunotherapy.
Life (Basel) 11:101. doi: 10.3390/life11020101.
Midha A, Ebner F, Schlosser-Brandenburg J, Rausch S, Hartmann S. (2021).
Trilateral relationship: Ascaris, microbiota, and host cells.
Trends Parasitol 37:251-62. doi: 10.1016/j.pt.2020.09.002.
Ebner F, Morrison E, Bertazzon M, Midha A, Hartmann S, Freund C, Álvaro-Benito M. (2020).
CD4+ Th immunogenicity of the Ascaris spp. secreted products.
NPJ Vaccines 5:25. doi: 10.1038/s41541-020-0171-z.
Ugolini M, Gerhard J, Burkert S, Jensen KJ, Georg P, Ebner F, Volkers SM, Thada S, Dietert K, Bauer L, Schäfer A, Helbig ET, Opitz B, Kurth F, Sur S, Dittrich N, Gaddam S, Conrad ML, Benn CS, Blohm U, Gruber AD, Hutloff A, Hartmann S, Boekschoten MV, Müller M, Jungersen G, Schumann RR, Suttorp N, Sander LE. (2018).
Recognition of microbial viability via TLR8 drives TFH cell differentiation and vaccine responses.
Nat Immunol 19: 386–96. doi:10.1038/s41590-018-0068-4.
Ebner F, Kuhring M, Radonić A, Midha A, Renard B, Hartmann S. (2018).
Silent witness: Dual-species transcriptomics reveals epithelial immunological quiescence to helminth larval encounter and fostered larval development.
Front Immunol 9:1868. doi: 10.3389/fimmu.2018.01868.
