Member since: April 2021

Research interest

Intestinal nematodes, infection intensity, flow cytometry and cell sorting, multiplexing

Title of PhD project
The role of antigen-specific T cells in the distribution and predisposition of Ascaris suum in pigs

Supervisor
Jun.-Prof. Dr. Friederike Ebner

Midha A, Oser L, Schlosser-Brandenburg J, Laubschat A, Mugo RM, Musimbi ZD, Höfler P, Kundik A, Hayani R, Adjah J, Groenhagen S, Tieke M, Elizalde-Velázquez LE, Kühl AA, Klopfleisch R, Tedin K, Rausch S, Hartmann S. (2024).
Concurrent Ascaris infection modulates host immunity resulting in impaired control of Salmonella infection in pigs.
mSphere Aug 14:e0047824. doi: 10.1128/msphere.00478-24.

Elizalde-Velázquez LE, Schlosser-Brandenburg J, Laubschat A, Oser L, Kundik A, Adjah J, Groenhagen S, Kühl AA, Rausch S, Hartmann S. (2024).
Th2-biased immune responses to body migrating Ascaris larvae in primary infection are associated with pathology but not protection.
Sci Rep 14:14919. doi: 10.1038/s41598-024-65281-0.

Mugo RM, Oser L, Midha A, Adjah J, Kundik A, Laubschat A, Höfler P, Musimbi ZD, Hayani R, Schlosser-Brandenburg J, Hartmann S, Rausch S. (2024).
Acute Ascaris infection impairs effector functions of natural killer cells in single and Salmonella co-infected pigs.
Sci Rep 14:14586. doi: 10.1038/s41598-024-64497-4.

Oser L, Midha A, Schlosser-Brandenburg J, Rausch S, Mugo RM, Kundik A, Elizalde-Velázquez LE, Adjah J, Musimbi ZD, Klopfleisch R, Helm CS, von Samson-Himmelstjerna G, Hartmann S, Ebner F. (2024).
Ascaris suum infection in juvenile pigs elicits a local Th2 response in a setting of ongoing Th1 expansion.
Front Immunol 15:1396446. doi: 10.3389/fimmu.2024.1396446.