Member since: Mai 2018

Research interest
drug resistance, xenobiotic metabolism, next generation sequencing

Title of PhD project
Identification and characterization of ML metabolic pathways in Cooperia oncophora

Supervisor
Dr. Jürgen Krücken

Jakobs N, Andreotti S, Ramünke S, von Samson-Himmelstjerna G, Krücken J. (2024).
Differences in constitutive gene expression of cytochrome P450 enzymes and ATP-binding cassette transporter gene expression between a susceptible and a highly macrocyclic lactone-resistant Haemonchus contortus isolate in the absence of drug-inducible expression.
Parasit Vectors 17:505. doi: 10.1186/s13071-024-06568-z.

Jakobs N, Yilmaz E, Krücken J. (2022).
Transgenic Expression of Haemonchus contortus Cytochrome P450 Hco-cyp-13A11 Decreases Susceptibility to Particular but Not All Macrocyclic Lactones in the Model Organism Caenorhabditis elegans.
Int J Mol Sci 23:9155 doi: 10.3390/ijms23169155.